Clinical Research cerebral MRI findings in HIV positive subjects and appropriate controls


Chhabra S, Underwood J, Cole JH, Waldman A, Sabin CA, Sharp DJ, Winston A

Lay summary

We used information that has been collected as part of brain scans performed among some participants in the POPPY study to study any abnormalities that may show up on these scans.  Whilst these brain abnormalities were relatively common (just under a half of scans showed an abnormality) there was no tendency for these abnormalities to be seen more often in people with HIV.  Rather, people with abnormalities tended to be those who were older and who had hypertension, suggesting that factors other than HIV are more likely to be to blame.  We did not find any association between these abnormal