Measurement of retinal vessels as a biomarker of cerebrovascular ageing in older HIV positive men compared to controls


Haddow LJ, Laverick R, Leung I, Gilson RC, Williams IG, Vera J, Post F, Boffito M, Sabin C, Winston A, Peto T.

Lay summary

Using photographs of the retina (back of the eye), it is possible to estimate the health of the small blood vessels in a person's brain. Ageing of these blood vessels has been linked to dementia and stroke. We took retinal photographs of men with HIV who were on effective treatment and HIV negative men in the POPPY study. Our study showed no difference between the health of the blood vessels in the men with HIV compared to the men without HIV.